Methylated cfDNA as a pathological biomarker for the development of a CRISPR/Cas based molecular diagnostic tool
Implementing Organization
BITS Pilani - Hyderabad Campus, Telangana
Innovator Details
Innovator
Prof. Deepak Chitkara
Co-Developer / Co-Innovator
Prof. Sunil Bhand, Senior Professor, Department of Chemistry
Prof. Ashis Kumar Das, Senior Professor, Department of Biological Sciences
About
This project aims to develop an early-stage diagnostic biosensor for chronic diseases like CKD, CVDs, and T2DM using CRISPR technology. By targeting cell-free DNA (cfDNA) methylation, the biosensor will detect disease progression through genetic analysis. Utilizing Cas12a effectors, it will enable precise, low-cost detection of biomarkers, facilitating early intervention and improving disease management.
BITS Pilani - Hyderabad Campus, Telangana
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