Problem: In India Leukaemia constitutes 25% of the hematopoietic malignancy, hence the need of the hour to design an indigenous Multiplex, viable prototype which is a quick, accurate, and thermally stable diagnostic assay for detection of two most common leukaemia’s, namely BCR-ABL1 (CML) and AML-ETO (AML) using TaqMan Probe.NEED: To design an affordable commercially viable prototype that detects and quantifies the control and transcript in a single vial on an international scale