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IN319972: Stereospecific and proficient synthesis of seven membered sulfide: its application for tamiflu synthesis

The invention discloses an economic, simple, azide and aziridine complexity free process for the synthesis of osletamivir phosphate (Tamiflu) by stereospecific amidoalkylation of imidazothiazolone from easily available L-cysteine via Ramberg-Backlund reaction and Sharpless-Reich protocol.
Patent No:
IN319972
Application No:
2956/DEL/2013
Filing Date:
04-10-2013
Issue Date:
06-09-2019
Applicant:
CSIR-National Chemical Laboratory (CSIR-NCL), Pune
Inventor(s):
Subhash Prataprao Chavan; Prakash; Narsing Chavan
IPC Classification:
C07D
Country:
India
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