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US9522922: Stereospecific and proficient synthesis of seven membered sulfide: its application for tamiflu synthesis

The invention discloses an economic, simple, azide and aziridine complexity free process for the synthesis of osletamivir phosphate (Tamiflu) by stereospecific amidoalkylation of imidazothiazolone from easily available L-cysteine via Ramberg-Backlund reaction and Sharpless-Reich protocol.
Patent No:
US9522922
Application No:
15/026,376
Filing Date:
31-03-2016
Issue Date:
20-12-2016
Applicant:
CSIR-National Chemical Laboratory (CSIR-NCL), Pune
Inventor(s):
Subhash Prataprao Chavan; Prakash Narsing Chavan
Country:
United States of America
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