US9777014: Tetrahydro-2h-Pyrano[3,2-C]Isochromene-6-Ones and analogs for the treatment of inflammatory disorders

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The present invention relates to 2,3,4,4a-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano[3,2-c]isochromen-6(10bH)-one analogs of the Formula I, wherein, R, R? and R? are as herein described. In addition, the invention relates to methods of using compounds for treating or preventing various inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma and chronic obstructive pulmonary disorder.

Patent No:: US9777014
Application No:: 14/891,706
Filing Date:: 17-11-2015
Issue Date:: 03-10-2017
Applicant:: CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu
Inventor(s):: Jain Shreyans Kumar; Sidiq Tabasum; Meena Samdarshi; Khajuria Anamika; Vishwakarma Ram Asrey; Bharate Sandip Bibishan
IPC Classification:: C07D 493/04
Country:: United States of America

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