IN300050: Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline
Abstract
Disclosed herein a novel, process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyL N-(1-methoxypropan-2-yt)-6-methyl aniline with excellent selectivity starting from commercially available enantiopure (R)-epichlorohydrin ((R)-2] via formation of aziridine intermediate [(S)-4].
Filing Date:
06-09-2012
Issue Date:
04-04-2014
Applicant:
CSIR-National Chemical Laboratory (CSIR-NCL), Pune
Patent No:
IN300050
Application No:
2768/DEL/2012
Inventor(s):
Murugan, Muthukrishnan; Mujumdar, Prashant Pramod
IPC Classification:
C07C
Country:
India
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