IN274930: A reusable thiophene end-capped bipyridine fluorescent assay for selective detection of cyanide anions in aqueous and biorelevant samples and process
Abstract
The invention describes the development of end-capped bipyridine compound and the zinc complex. The assay can be used to estimate and quantify the amount of zinc ions by monitoring the fluorescence changes. The assay can be used to image and detect Zn2+ ions in MCF7 cell lines. The zinc complex can be used as a fluorescent sensor for cyanide anions using analyte replacement protocol. The assay is selective only to cyanide anions even in the presence of other competing anions. The assay having bright green solid state emission is used for the preparation. The orange fluorescent powder of assay is used for the selective detection of CN- ions in aqueous solution.
Filing Date:
15-09-2009
Issue Date:
13-08-2016
Applicant:
CSIR-National Institute for Interdisciplinary Science and Technology (NIIST), Thiruvananthapuram
Patent No:
IN274930
Application No:
1899DEL2009
Inventor(s):
Ayyapanpillai Ajayaghosh, Sivaramapanicker Sreejith, Kizhumuri P. Divya, Puroshothaman Jayamurthy
IPC Classification:
C07D 401/14
Country:
India
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