IN314002: A synthetic peptide formulation against melanoma and other cancers over-expressing s100b
Abstract
The invention describes a novel bivalent helically constrained peptide targeted against S100B that is an effective anti-cancer drug against cancers that over-express S100B. This helix mimetic targeted against S100B induces rapid apoptosis in cancer cells that over-express a calcium binding protein S100B through simultaneous inhibition of key growth pathways including activation of p53.
Filing Date:
31-01-2011
Issue Date:
11-06-2019
Applicant:
CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata
Patent No:
IN314002
Application No:
0207DEL2011
Inventor(s):
Amlanjyoti Dhar, Shampa Mallick, Israr Ahmed, Aditya Konar, Santu Bandyopadhyay, Siddhartha Roy
IPC Classification:
A61K38/00, C07K14/00,
Country:
India
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