IN289555: An improved process for the eco-friendly preparation of 3,5-dibromo-4-hydroxybenzonitrile
Abstract
A highly pure 3,5-dibromo-4-hydroxybenzonitrile (bromoxynil) has been prepared in high yield from 4-hydroxybenzonitrile using eco-friendly brominating reagent comprising of 2:1 mole ratio of bromide to bromate salts in aqueous acidic medium without any catalyst under ambient conditions with no workup procedure. The product 3,5-dibromo-4-hydroxybenzonitrile was obtained in 91-99% yield with melting point 189-191°C and more than 99% purity by gas chromatographic analysis without any purification.
Filing Date:
25-02-2009
Issue Date:
14-11-2017
Applicant:
CSIR-Central Salt and Marine Chemicals Research Institute (CSIR-CSMCRI), Bhavnagar
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