10-substituted colchicinoids as potent anticancer agents

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The invention relates to the compounds of Formula I wherein R1 and R2 are as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10- substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease.

Patent No:: IN370382
Application No:: 2929DEL2014
Filing Date:: 14-10-2014
Issue Date:: 27-06-2021
Applicant:: CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu
Inventor(s):: Vishwakarma Ram, Bharate Sandip Bibishan, Kumar Ajay, Singh Baljinder, Kumar Ashok, Bhushan Shashi, Hamid Abid, Joshi Prashant, Guru Santosh Kumar, Kumar Suresh, Hussain Aashiq, Qazi Asif Khurshid, Bharate Sonali Sandip, Sharma Parduman, Saxena Ajit Kumar, Mondhe Dilip Manikrao, Mahajan Girish, Wani Zahoor
Country:: India

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