IN365339: 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereofanti-mycobacterial agents

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The invention relates to newer generation of triazoles, tetrazoles, isoxazoles, urea and sulphonamide functionalities containing 6-nitro-2, 3-dihydronitroimidazooxazoles agents of formula 1, their method of preparation, and their use as drugs for treating Mycobacterium tuberculosis,MDR-TB and XDR-TB either alone or in combination with other anti-tubercular agents. In this invention, new generation 6-nitro-2, 3-dihydronitroimidazooxazoles agents also show acceptable pharmacokinetic properties and synergistic or additive effects with known anti-tubercular drugs.

Patent No:: IN365339
Application No:: 2954DEL2013
Filing Date:: 04-10-2013
Issue Date:: 26-04-2021
Applicant:: CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu
Inventor(s):: Parvinder Pal Singh, Gurunadham Munagala, Kushalava Reddy Yempalla, Inshad Ali Khan, Nitin Pal Kalia, Vikrant Singh Rajput, Amit Nargotra, Sanghapal Damodhar Sawant, Ram Asrey Vishwakarma
Country:: India

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