US10947248: 4beta-Amidotriazole Linked Podophyllotoxin Derivatives As Potential Anticancer Agents

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The invention relates to a compound of general formula (A). The invention provides a synthesis of new 4?-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof. Wherein n=0, 1 and R1-R5=[H, CI, F, CH3, OCH3, 3,4(-OCH2O—), CF3, OCF3, m-OC6H5, OH]

Patent No:: US10947248
Application No:: 16/084162
Filing Date:: 11-09-2018
Issue Date:: 16-03-2021
Applicant:: CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad
Inventor(s):: Ahmed Kamal, Velma Ganga Reddy, Ayinampudi Venkata Subbarao, Syed Riyaz, Vadithe Lakshma Nayak, Shaik Taj
IPC Classification:: C07D 493/04, A61P 31/12, A61P 35/00
Country:: United States of America

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