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IN372693: 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors

The invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R" are as herein described. The invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-a (PI3K-a) inhibitory activity. In addition, the invention relates to methods of using compounds for treating or preventing various cancers such as pancreatic, prostate, breast and melanoma.
Patent No:
IN372693
Application No:
0554DEL2014
Filing Date:
27-02-2014
Issue Date:
30-07-2021
Applicant:
CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu
Inventor(s):
Vishwakarma Ram Asrey, Bharate Sandip Bibishan, Bhushan Shashi, Yadav Rammohan Rao, Guru Santosh Kumar, Joshi Prashant
IPC Classification:
H01Q
Country:
India
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