IN372693: 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors

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The invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R" are as herein described. The invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-a (PI3K-a) inhibitory activity. In addition, the invention relates to methods of using compounds for treating or preventing various cancers such as pancreatic, prostate, breast and melanoma.

Patent No:: IN372693
Application No:: 0554DEL2014
Filing Date:: 27-02-2014
Issue Date:: 30-07-2021
Applicant:: CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu
Inventor(s):: Vishwakarma Ram Asrey, Bharate Sandip Bibishan, Bhushan Shashi, Yadav Rammohan Rao, Guru Santosh Kumar, Joshi Prashant
IPC Classification:: H01Q
Country:: India

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