US8927560: 4-aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof

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The invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines and further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae).

Patent No:: US8927560
Application No:: 13/522219
Filing Date:: 13-07-2012
Issue Date:: 06-01-2015
Applicant:: CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad
Inventor(s):: Ahmed Kamal, Paidakula Suresh, Banala Ashwini Kumar, Adla Mallareddy, Papagari Venkat Reddy, Jaki Rasheed Tamboli
IPC Classification:: A61K 31/505, C07D 498/00, C07D 261/20, C07D 487/00, C07D 471/00, C07D 239/00, C07D 491/00, A61K 31/44, A01N 43/42, A01N 43/54
Country:: United States of America

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