IN341911: A highlyenantioselective synthesis of (+)-sertraline
The invention discloses substituted diphenyloxiranes and process for synthesis thereof. The present invention also provides a process for production of enantiomerically pure anti - 3,3-diphenylmethyloxirane and anti-3,3’-diphenylpropane-1,2-diol from racemic anti -3,3’-diphenylmethyloxirane using hydrolytic kinetic resolution. Further it provides a process for preparation of enantioselective (+) -Sertraline from anti - 3,3’ –dipheny lpropane-1,2-diol.
Patent No:
IN341911
Application No:
3482DEL2014
Filing Date:
01-12-2014
Issue Date:
17-07-2020
Applicant:
CSIR-National Chemical Laboratory (CSIR-NCL), Pune
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