Patents

Disclosed herein an efficient process for synthesis of benzofuran analogues having anti inflammatory activity which comprises Ru catalyzed branched and linear selective alkylation of aroylbenzofurans formula I with alpha beta unsaturated esters of formula II via C H activation in presence of base additives and organic solvent at suitable temperature to give high yield of desired linear alkylated  benzofuran compounds of formula III or branched alkylated benzofuran compounds of formula IV or mixture thereof.