Patents

The invention provides a bio-active composition obtained from Boswellia species, exhibiting in vivo and in vitro anti-cancer activity. The bio-active composition comprises an isomeric mixture of 3 a, 24-dihydroxyurs-12-ene and 3a, 24-dihydroxyolean-12-ene in the ratio of 1:20 to 1:1, optionally along with pharmaceutically acceptable carriers or additives. The pharmaceutically effective dose of the said composition is in the range of 250 -lOOOmg/Kg body weight of a subject. The composition is isolated after repeated column chromatography of the neutral extract of the gum resin of Boswellia serrata and related natural sources and can be alternatively prepared from semi-synthetic source. The said composition exhibits anti-cancer activities for breast, leukemia, liver, and colon and brain cancer.