Patents

An efficient process was developed for the synthesis of fragrant compound, Mefrosol in a two-step process. The first step relates to a  process for producing dihydropyran compound, Rosyrane by reacting benzaldehyde with 3-methyl-3-butene-l-ol using toluene as a solvent in presence of acidic resin based catalyst. The second step involves the hydrogenation and hydrogcnolyis of the dihydropyran  compound using simple Pd/C catalyst. The inventions discloses the use of simple catalysts having excellent conversion and  selectivity towards the desired product in both the steps under optimized condition. The process represents an alternative  method to the previously reported procedures and eliminates the use of additional additives. The catalyst used in the first step is  recyclable upto 10 times with the retention of its activity.