IN359748: A process for the synthesis of ivacaftor and related compounds

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The patent discloses a novel one-pot, two-step process for the synthesis of ivacaftor and related compounds of [Formula (I)], wherein R1, R2, R3, R4, R5, R6, R7 and Ar1 are as described above; its tautomers or pharmaceutically acceptable salts thereof starting from indole acetic acid amides.

Patent No:: IN359748
Application No:: 1324DEL2015
Filing Date:: 12-05-2015
Issue Date:: 26-02-2021
Applicant:: CSIR-National Chemical Laboratory (CSIR-NCL), Pune
Inventor(s):: Dumbala Srinivasa Reddy, Vasudevan Natarajan, Gorakhnath Rajaram Jachak
Country:: India

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