US8748660: Process for the synthesis of antiepileptic drug lacosamide

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The invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the invention relates to improved and efficient, cost-effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether.

Patent No:: US8748660
Application No:: 13/589923
Filing Date:: 20-08-2012
Issue Date:: 10-06-2014
Applicant:: CSIR-National Chemical Laboratory (CSIR-NCL), Pune
Inventor(s):: Muthukrishnan Murugan; Mohammad Mujahid; Prashant Pramod Majumdar
IPC Classification:: C07C 233/05, C07C 231/08
Country:: United States of America

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