IN337658: An antioxidant compound having anti atherosclerotic effect and preparation thereof
The invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The invention more particularly relates to the synthesis of TPP+ coupled esculetin (Mitochondria-targeted esculetin [Mitb-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-11-induced atherosclerosis in apolipoproteinE knockout (ApoE/_) mice along with the endothelial cell age-delaying effects of Mito-Esc.
Patent No:
IN337658
Application No:
0478DEL2015
Filing Date:
19-02-2015
Issue Date:
29-05-2020
Applicant:
CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad
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