US8841466: Series of artemisinin derivatives and process for preparation thereof
This invention relates to the synthesis of certain novel Baylis-Hillman adducts of artemisinin-derived aldehyde 2-[10'?-deoxoartemisininyl]-ethanal. The capabilities of introduction of three functional groups into a molecule in one step using the Baylis-Hillman reaction encouraged us to synthesize some highly functionalized derivatives of artemisinin. These highly functionalised artemisinin derivatives embodied in this document are found to be active against various cancer cell-lines.
Patent No:
US8841466
Application No:
13/574440
Filing Date:
15-10-2012
Issue Date:
23-09-2014
Applicant:
CSIR-North East Institute of Science and Technology (CSIR-NEIST), Jorhat
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