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IN359021: Silver nitroprusside nanoparticles and a process for the preparation thereof

The invention relates to silver nitroprusside nanoparticles (Ag2[Fe(CN)5NO]) and a process for the synthesis of silver nitroprusside nanoparticles (Ag2[Fe(CN)5NO]) having biomedical applications. The nanoparticles (AgSNPs) have been thoroughly characterised by several physiochemical techniques. These nanoparticles (AgSNPs) showed significant inhibition of the proliferation of different cancer cells in an in-vitro system and significant wound healing in the punch biopsy model in C57/BL6 mice. Additionally, the AgSNPs showed enhanced anti-bacterial activity towards gram-negative (Escherichia coli, Klebsiella aerogenes, monas aeruginosa) and gram-positive (Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis) bacteria.
Patent No:
IN359021
Application No:
201611039557
Filing Date:
21-11-2016
Issue Date:
22-02-2021
Applicant:
CSIR-Indian Institute of Chemical Technology (CSIR-IICT)
Inventor(s):
Bonda Rama Rao; Susheel Kumar Nethi; Rajesh Kotcherlakota; Chitta Ranjan Patra
IPC Classification:
A61K
Country:
India
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