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Clinical and sero-epidemiological study of scrub typhus, spotted fever and Q fever in Puducherry

Implementing Organization

Principal Investigator
Dr. Selvaraj Stephen
Professor, Mahatma Gandhi Medical College and Research Institute (MGMC and RI), Pondicherry
CO-Principal Investigator
Dr. Mohamed Hanifah
Professor, Mahatma Gandhi Medical College and Research Institute (MGMC and RI), Puducherry, Dr. Dhandapany Gunasekaran, Professor, Mahatma Gandhi Medical College and Research Institute (MGMC and RI), ) Puducherry, 607403, Dr. Prabakhar Xavier Antony (Associate Professor, Rajiv Gandhi College of Veterinary and Animal Sciences (RGCVAS), Puducherry,Tamil Nadu, Dr. Kengamuthu Sarangapani, Scientist, Indira Gandhi Govt. General Hospital and Post Graduate Institute (IGMCRI), Pondicherry, Dr. Stanley A

Project Overview

Pondicherry and neighbouring Tamil Nadu has become ST endemic areas. Hence for Scrub typhus diagnosis, reliance should be placed on IgM ELISA rather than WF (OXK) and single OXK titres up to 1:160 should not be considered as significant. As reported earlier (2013), rapid ST ICT kits are specific and far superior to WF. We have also proved the unreliability of three commercial ELISA kits for C. burnetii Phase II IgM. Hence use of these kits should be discouraged and to be replaced by IFA and to be preferably confirmed by PCR. Regarding Q fever, physicians were initially unaware of this clinical entity, but now are sensitized to look for common symptoms of acute Q fever as well as the chronic forms of Q fever. Coxiellosis in domestic livestock has been found to be low.
Funding Organization
Funding Organization
Indian Council of Medical Research (ICMR), New Delhi
Quick Information
Area of Research
Medical Sciences
Focus Area
Microbiology
Start Date
2012
End Date
2015
Status
Completed
Contact
stephens4950@gmail.com;hanifah4u@yahoo.com;drguna007@yahoo.co.uk;pxantony@gmail.com;drksarangapani@yahoo.com;ashambroise@hotmail.com
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
02
No. of Patents
Filed : 00
Grant : 00
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