Effect of 5% human albumin-based perioperative fluid therapy in perforation peritonitis patients undergoing emergency laparotomy: A randomized controlled trial

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Implementing Organization

All India Institute of Medical Sciences

Principal Investigator

Dr Sulagna Bhattacharjee

Assistant Professor, All India Institute of Medical Sciences (AIIMS), Delhi

CO-Principal Investigator

Dr Rahul Kumar Anand

Assistant Professor, All India Institute of Medical Sciences (AIIMS), Delhi

Project Overview

The primary objective of this study is to know the effect of 5% human albumin-based perioperative fluid therapy on postoperative endothelial glycocalyx shedding product, i.e. syndecan- 1, over isotonic balanced salt solutions. The secondary objective is to compare postoperative hyaluronan, heparan sulphate, ANP, TNF-a, IL-1, IL-6 and IL-10 in these two groups of patients. Along with the duration of ICU stay, duration of hospital stay and hospital mortality will be noted.

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Funding Organization

Funding Scheme

Core Research Grant (CRG)

Funding Organization

Department of Science and Technology (DST)

Quick Information

Area of Research

Medical Sciences

Focus Area

Fluid management

Start Date

2022

Status

ongoing

Contact

bhattacharjee.sulagna85@gmail.com

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

Publications

No. of Patents

Filed : 00

Grant : 00

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Research Projects