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Identifying the molecular marker(s) for relapse malaria in the Plasmodium vivax

Implementing Organization

National Institute of Malaria Research Delhi (NIMR), New Delhi 110077
Principal Investigator
Dr. Ram Das
Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi
CO-Principal Investigator
Dr. RC Dhiman
Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi, 110077
CO-Principal Investigator
Dr. AR Anvikar
Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi, Dr. D Savargaonkar, Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi, Dr. N Mishra, Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi, 110077, Dr. N Valecha, Scientist, National Institute of Malaria Research Delhi (NIMR), New Delhi

Project Overview

Study provided evidence of differentiating relapse and reinfection in P. vivax by newly designed minisatellite markers. These newly designed minisatellite markers are high polymorphic nature. This technique is simple, rapid, cost effective as compared to PCR-RFLP, sequencing, GeneMaper and heteroduplex systems. Minisatellite markers may also be applicable for allelic determination for field studies in areas having high vivax malaria. Genotyping of P. vivax by minisatellite marker has potential to link the infections in community-based studies on relapse, reinfection and transmission of disease also. The generated genotyping data in this study suggest that minisatellite markers are a potential tool to help, drug trial and evolutionary changes within P. vivax strains.
Funding Organization
Funding Organization
Indian Council of Medical Research (ICMR), New Delhi
Quick Information
Area of Research
Medical Sciences
Focus Area
Malaria
Start Date
2015
End Date
2016
Status
Completed
Contact
drrdas_3@yahoo.co.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
02
No. of Patents
Filed : 00
Grant : 00
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