Investigating the mechanism of Insulin-dependent regulation of RAB4-associated vesicular transport in axons
Implementing Organization
Tata Institute of Fundamental Research (TIFR)
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Principal Investigator
Prof. Krishanu Ray
Professor, Tata Institute of Fundamental Research (TIFR), Mumbai
Project Overview
This project proposes to employ a combination of in vitro and in vivo approaches to identify a) how RAB4 recruits kinesins after insulin stimulation, b) how RAB4 vesicles move with an increased speed upon insulin stimulation, and c) the effects of the increased flux of RAB4 vesicle movement on the synapse homeostasis.
Professor, Tata Institute of Fundamental Research (TIFR), Mumbai
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