Investigation on the mode of substrate addition with reference to some steroid biotransformation reactions

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Implementing Organization

North Eastern Hill University Visit

Principal Investigator

Dr. Timir Tripathi

Assistant Professor, North Eastern Hill University (NEHU), Shillong, Meghalaya

Project Overview

The thiol-based redox-sensitive proteins of the F. giganticamitochondrial Trx (FgTrx2) is of 16kDa, whereas FgTrx1 is 11.5 kDa molecular weight with active site –WCTPC-, while the other mitochondrial Trx have –WCGPC- or –WCNPC-, none of mitochondrial Trx have –WCTPC- active site motif. Presently, the redox reaction metabolism signifies an important for drug target development, and it has not been studies elaborately in any platyhelminthic parasitic. Hear we plane to characterize FgTrx2 protein in detail to understand the redox biology of this neglected tropical parasite.

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Funding Organization

Indian Council of Medical Research (ICMR), New Delhi

Quick Information

Area of Research

Medical Sciences

Focus Area

Biochemistry

Start Date

2015

End Date

2016

Status

Completed

Contact

ttripathi@gmail.com

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

Publications

No. of Patents

Filed : 00

Grant : 00

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