Vitamin D supplementation for severe pneumonia in under-five children: A double blind, randomized placebo controlled trial

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Implementing Organization

University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi 110095

Principal Investigator

Dr. Piyush Gupta

Professor, University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi

CO-Principal Investigator

Dr. Dheeraj Shah Professor

University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi, Professor, University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi, Director-Professor and Head, Division of Endocrinology and University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi, Dr. Iqbal R Kaur, Professor and Head, University College of Medical Sciences (UCMS) and GTB Hospital, New Delhi, Sr. Programmer-cum-Statistician, University College of Medical Sciences (UCMS) and GTB Hospi

Project Overview

A single oral dose of 100,000 IU Vitamin D3 supplementation given during the episode of severe pneumonia marginally improves the chances of early resolution of severe pneumonia without any clinically significant effect on the duration of illness; and specific or non-specific immune markers. The intervention does not prevent the recurrence of pneumonia in next six months, despite an improvement in vitamin D status in the supplemented group. We conclude that there is no robust evidence of a definite biological benefit to suggest a routine megadose supplement for under-five children with severe pneumonia.

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Funding Organization

Indian Council of Medical Research (ICMR), New Delhi

Quick Information

Area of Research

Medical Sciences

Focus Area

Child Health

Start Date

2012

End Date

2015

Status

Completed

Contact

prof.piyush.gupta@gmail.com;shahdheeraj@hotmail.com;poojadewan@hotmail.com;svmadhu@gmail.com;iqbalrk@yahoo.com;akchbansal@yahoo.com

Output

No. of Research Paper

Technologies (If Any)

No. of PhD Produced

Publications

No. of Patents

Filed : 00

Grant : 00

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