Deciphering the redox chemistry of physical plasma-treated clinically-relevant liquids as novel therapy against ovarian cancer
Implementing Organization
Principal Investigator
Dr. Naresh Kumar
Ramalingaswami fellow, National Institute of Pharmaceutical Education and Research (NIPER-G), Guwahati
CO-Principal Investigator
Dr. BidyaDhar Sahu
National Institute of Pharmaceutical Education and Research (NIPER-G), Guwahati
Project Overview
This project aims to identify the optimal tumor-toxic target chemistry of plasma-treated liquids (PTL) as anticancer agents. The project will use clinically-relevant liquids and experimental methods to optimize plasma redox chemistry. The PTLs will be tested in vitro for efficacy in treating metastatic ovarian cancer, a common cancer in young women. The molecular basis of anticancer PTL redox effects will be investigated, and the best plasma condition will be investigated for pre-clinical impact. The novel redox-active PTL approach will be tested in mice.
Ramalingaswami fellow, National Institute of Pharmaceutical Education and Research (NIPER-G), Guwahati
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