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HPV Associated Cervical Cancer early screening kit development

Implementing Organization

National Institute of Technology (NIT), Arunachal Pradesh
Principal Investigator
Dr. Saikat Kumar Jana
National Institute of Technology (NIT), Arunachal Pradesh
saikatmicro4@gmail.com
Principal Investigator
Dr. Suvankar Ghorai
Raiganj University, Raiganj, West Bengal
suvankarbt@gmail.com
CO-Principal Investigator
Dr. Ranajit Mandal
Chittaranjan National Cancer Institute, Kolkata
kranajitmandal@yahoo.co.in
CO-Principal Investigator
Dr. Murugan Veerapandian
Central Electrochemical Research Institute, Karaikudi, Tamil Nadu
momugan@gmail.com
CO-Principal Investigator
Dr. Debabrata Barmon
B. Borooah Cancer Institute, Guwahati, Assam
drdbarmon@gmail.com

Project Overview

Cervical cancer is the second most common cancer worldwide and one of the gravest threats to women’s lives. Current screening programs require extensive healthcare systems, regular access to trained health professionals, and validated laboratories capable of providing standardized pathological diagnoses. Here we proposed to identify specific peptide /aptamer-based electrochemical /paper diagnostic devices is an affordable, non-intrusive, real-time test for cervical cancer for the detection of HPV from biological fluids.

Achievements

Successfully collected and PCR-confirmed clinical samples (urine and vaginal swabs) from HPV-positive and healthy individuals across Northeast India. Developed two electrochemical immunosensors targeting HPV16 E7 and HPV18/16L1 proteins with ultra-sensitive detection limits. Demonstrated the use of a gold-graphitic carbon nitride (Au-g-C₃N₄) nanocomposite and gold nanoparticle-enhanced electrodes for high-specificity biosensing. Completed morphological and electrochemical characterization of sensor platforms(SEM,TEM,XRD, CV, SWV, and EIS), ensuring high reproducibility and analytical performance.

Source

Source
E-promis and Information received by Investigator

Related Research

View All
Funding Organization
Funding Organization
Department of Science and Technology (DBT)
Quick Information
Area of Research
Medical Sciences
Focus Area
Cancer Diagnostics
Start Date
04 Mar 2022
End Date
03 Apr 2025
Status
Completed
Email
saikatmicro4@gmail.com
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
01
No. of Patents
Filed : 00
Grant : 00
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