Development of macro-encapsulation device for islet cell transplantation for diabetes treatment
Implementing Organization
Indian Institute of Technology (IIT)
Asian Institute of Gastroenterology, Hyderabad
Principal Investigator
Subha Narayan Rath
Associate Professor
|
Indian Institute of Technology (IIT), Hyderabad
Dept. of Biomedical Engineering
CO-Principal Investigator
Dr R Pradeep
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr R Talukdar
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr M Sasikala
Head (Research)
|
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr D Nageshwar Reddy
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Chandra Sekhar Sharma
Associate Professor
|
Indian Institute of Technology (IIT), Hyderabad
CO-Principal Investigator
Dr GV Rao
Asian Institute of Gastroenterology, Hyderabad
About
We plan to indigenously develop a macroencapsulation device for cellular therapy, especially islet transplantation in the management of uncontrolled diabetes. The basic aim is to use allogenic or xenogeneic cells in a macroencapsulation device in which, the cells secrete the required proteins without being affected by host immune cells attacking them. The porous chamber should allow the smaller protein molecules to pass out and nutrients like glucose, amino acids to pass in; but should not let the bigger immune cells to enter into the device.
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