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Development of macro-encapsulation device for islet cell transplantation for diabetes treatment

Implementing Organization

Indian Institute of Technology (IIT)
Asian Institute of Gastroenterology, Hyderabad
Principal Investigator
Subha Narayan Rath
Associate Professor
|
Department of Mechanical and Aerospace Engineering, Indian Institute of Technology (IIT), Hyderabad, Telangana
Dept. of Biomedical Engineering
CO-Principal Investigator
Dr R Pradeep
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr R Talukdar
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr M Sasikala
Head (Research)
|
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Dr D Nageshwar Reddy
Asian Institute of Gastroenterology (AIG), Hyderabad
CO-Principal Investigator
Chandra Sekhar Sharma
Associate Professor
|
Indian Institute of Technology Hyderabad
CO-Principal Investigator
Dr GV Rao
Asian Institute of Gastroenterology, Hyderabad

Project Overview

We plan to indigenously develop a macroencapsulation device for cellular therapy, especially islet transplantation in the management of uncontrolled diabetes. The basic aim is to use allogenic or xenogeneic cells in a macroencapsulation device in which, the cells secrete the required proteins without being affected by host immune cells attacking them. The porous chamber should allow the smaller protein molecules to pass out and nutrients like glucose, amino acids to pass in; but should not let the bigger immune cells to enter into the device.

Related Research

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Funding Organization
Funding Organization

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Quick Information
Area of Research
Material Sciences
Focus Area
Materials for better health/health services
Sanction Amount
₹ 1.27 Cr
Status
Ongoing
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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