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Understanding the role of SARS-CoV-2 virulence factor-Orf3a in modulating host cell responses: A way to identify host-directed therapy

Implementing Organization

Principal Investigator
Dr Amit Tuli
Scientist, CSIR-Institute of Microbial Technology, Chandigarh

Project Overview

The aim of this grant application is to understand the role of SARS-CoV-2 Orf3a in modulating host cell responses. To achieve this, the following objectives will be pursued: (i) determine Orf3a localisation in host cells and delineate sorting motifs required for its intracellular trafficking; and (ii) elucidate the significance of Orf3a interaction with candidate host endosomal-lysosomal proteins.

Achievements

NA
Funding Organization
Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Therapeutics for COVID-19
Start Date
2020
Contact
atuli@imtech.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
Publications
01
No. of Patents
Filed : 00
Grant : 00
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