Development of SERS based ultra-sensitive, rapid, portable and field deployable platform for detection of pathogenic bacteria and Dengue virus
Implementing Organization
Institute of Technology (IIT), New Delhi
National Institute of Malaria Research (NIMR), New Delhi
Principal Investigator
Dr. J.P. Singh
Professor
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Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology (IIT), New Delhi, India
Department of Physics
CO-Principal Investigator
Dr. Neena Valecha
Director & Scientist-G
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National Institute of Malaria Research (NIMR), New Delhi
CO-Principal Investigator
Dr. Deepali Savargaonkar
Scientist-D
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National Institute of Malaria Research (NIMR), New Delhi
CO-Principal Investigator
Prof. Prashant Mishra
Professor
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Department of Biochemical Engineering & Biotechnology, Indian Institute of Technology (IIT), New Delhi, India
Biochemical Engineering and Biotechnology
Project Overview
A new handheld, field-deployable SERS based diagnostic tool having capabilities of rapid on-chip specimen separation and detection of Dengue virus and pathogenic bacteria like Staphylococcus aureus and Escherichia coli for point-of-care diagnostics will be developed. The current available methods for identification of bacteria/virus such as biochemical test, PCR are time consuming and laborious. The novel Ag nanorod based surface enhanced Raman scattering substrates fabricated by e-beam glancing angle deposition (GLAD) system will provide rapid and accurate detection of pathogenic bacteria and dengue virus. The hypothesis is that SERS spectrum provides a unique 'molecular fingerprint' of individual virus/bacteria based on their specific molecules that are in contact with metal nanoparticles without any species-specific reagents typically required for virus/bacteria signal amplification.
Institute of Technology (IIT), New Delhi
Professor
Department of Physics
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