Scientist, CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata
Objective: Communication of anti-inflammatory signal from infected macrophage to neighboring cells: Effect on niche creation for Ld infection. Evaluating the potential of host derived Wnt in promoting resistance to Leishmania donovani infection. Cholesterol induced modulation of the leishmanial KMP-11 protein-macrophage interaction. Role of Leishmania derived linoleate in immunoregulation of macrophage. Role of Leishmania y-glutamyl cyclotransferase (ChaC) like protein in pathogenesis of this parasite. Understanding the genome fluidity during the process of gain or loss of virulence in Leishmania.
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