×

img Accessibility Controls

Research Projects Banner

Research Projects

Non-alcoholic fatty liver disease (NAFLD): Novel pathogenic mechanism and therapeutic development

Implementing Organization

Principal Investigator
Dr Partha Chakrabarti
Scientist, CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata

Project Overview

Objective: Role of Ubiquitin-proteasome system (UPS) in the pathogenesis of NAFLD; Role of non-coding RNA in NAFLD; ER stress - Mitochondrial dysfunction - Autophagy triad during progression of NAFLD and to NASH; Targeted small molecule inhibitors for treatment of NAFLD by preventing ATGL degradation; Development of Novel mTOR inhibitors for reduction of lipogenesis and lipid accumulation in Hepatocytes; Identification of potential leads from Indian traditional medicinal plants against NAFLD.

Funding Organization
Quick Information
Area of Research
Medical Sciences
Focus Area
Non-alcoholic fatty liver disease
Start Date
2020
End Date
2025
Status
Completed
Contact
director@iicb.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
00
No. of Patents
Filed : 00
Grant : 00
arrowtop
Latest Updates
Loading…