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Seroepidemiology, matenal immun status and missed diagnosis of pertussis in India- A multicentric study

Implementing Organization

Principal Investigator
Dr Rajlakshmi Viswanathan
Scientist, National Institute of Virology (NIV), Pune

Project Overview

This project has been developed to study the impact of maternal immune status on infant susceptibility to pertussis through a multicentre seroepidemiological and surveillance study.India alone has contributed 37,274 pertussis cases to the global burden in 2016. Despite this, very little information on pertussis is available from India in recent years. Diagnosis of pertussis largely remains clinical, as laboratory services are usually not available except in a few apex institutions .A recent multinational serosurveillance study, conducted in ten Asian countries, including India demonstrated serologic evidence of significant circulation of B. pertussis amongst Asian children and adolescents regardless of vaccination background. There is therefore an urgent need to further study the seroepidemiology of pertussis in general population and pregnant women and generate evidence for identification of age groups which may potentially benefit from booster immunizationsThe study will also generate information on pertussis immunity among different age groups, focusing on adolescents and women of child bearing age. Laboratory capacity for pertussis diagnostics will be strengthened through implementation of this project.

Achievements

Medical microbiologist with experience of establishing laboratory networks,contributed to understanding antimicrobial resistance in neonatal sepsis, estimation of birth prevalence of congenital CMV infection ,experience of outbreak investigation as a public health microbiologist
Funding Organization
Funding Organization
The Wellcome Trust/DBT India Alliance H. No. 8-2-684/3/K/19, 1st Floor, Kaushik Society Road No. 12, Banjara Hills, Hyderabad - 500034 Telephone No : +91 40 4018 9445 / 6 / 7 Fax : +91 40 4018 9449
Quick Information
Area of Research
Medical Sciences
Focus Area
Infections of fetus, neonate and pediatric age groups
Start Date
2019
End Date
2024
Sanction Amount
₹ 29.70 L
Status
Completed
Contact
rupamicro11@gmail.com
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
Publications
28
No. of Patents
Filed : 00
Grant : 00
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