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Development of SERS based ultra-sensitive, rapid, portable and field deployable platform for detection of pathogenic bacteria and Dengue virus

Implementing Organization

Principal Investigator
Dr. J.P. Singh
Professor, Department of Physics, Indian Institute of Technology (IIT), New Delhi
CO-Principal Investigator
Prof. Prashant Mishra
Professor, Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT), New Delhi, Dr. Neena Valecha, Director & Scientist-G, National Institute of Malaria Research (NIMR), New Delhi, Dr. Deepali Savargaonkar, Scientist-D, National Institute of Malaria Research (NIMR), New Delhi

Project Overview

A new handheld, field-deployable SERS based diagnostic tool having capabilities of rapid on-chip specimen separation and detection of Dengue virus and pathogenic bacteria like Staphylococcus aureus and Escherichia coli for point-of-care diagnostics will be developed. The current available methods for identification of bacteria/virus such as biochemical test, PCR are time consuming and laborious. The novel Ag nanorod based surface enhanced Raman scattering substrates fabricated by e-beam glancing angle deposition (GLAD) system will provide rapid and accurate detection of pathogenic bacteria and dengue virus. The hypothesis is that SERS spectrum provides a unique 'molecular fingerprint' of individual virus/bacteria based on their specific molecules that are in contact with metal nanoparticles without any species-specific reagents typically required for virus/bacteria signal amplification.
Funding Organization
Quick Information
Area of Research
Medical Sciences
Focus Area
Maternal and child health, Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases
Sanction Amount
₹ 1.22 Cr
Contact
jpsingh[at]physics[dot]iitd[dot]ac[dot]in; pmishra[at]dbeb[dot]iitd[dot]ac[dot]in; director[at]mrcindia[dot]org;
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
Publications
00
No. of Patents
Filed : 00
Grant : 00
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