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To study gene expression for vitamin d receptor (VDR) and calcium sensing receptor (CaSR) in patients with primary hyperparathyroidism (PHPT) and its correlation with clinical outcome

Implementing Organization

Principal Investigator
Dr. Sanjay Kumar Bhadada
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012
CO-Principal Investigator
Dr. Madhu Khullar
Professor
|
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012
CO-Principal Investigator
Dr. Uma Nahar Saikia
Additional Professor
|
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012
CO-Principal Investigator
Dr. Naresh Sachdeva
Assistant Professor
|
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012

About

The present findings showed significant reductions in VDR mRNA expressions in adenomatous compared to normal parathyroid tissue. Consistent with these, immunohistochemistry also revealed reduction at both nuclear as well as cytoplasmic expression in adenoma cells.

Achievements

Research fellows 02

Outcome / Output

The present findings showed significant loss of CaSR expression at mRNA and protein level in parathyroid adenomas.

Publications

3

Related Research

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Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Nutrition
Start Year
2010
End Year
2012
Sanction Amount
₹ NA
Status
Completed
Contact
bhadadask@rediffmail.com;
khullar.madhu@pgimer.edu.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
1
No. of Patents
Filed : 00
Grant : 00
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