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Studies of antioxidative and immunomodulatory effect of conjugated linolenic acid from bitter gourd oil

Implementing Organization

University of Calcutta
Principal Investigator
Dr. Pubali Dhar
Professor
|
University of Calcutta
CO-Principal Investigator
Dr. Prasanta K Bag
Professor
|
University of Calcutta

Project Overview

The mode of CLnA implementation in the biological models was modified to nanoemulsion and conventional formulations for better absorption, lesser auto-oxidation and providing technological dimension for pragmatic and clinical relevance. Methodology developed can also be commercialized as a low cost high impact technology for similar studies on bioactive lipids. Emphasis was laid on providing empirical evidence to establish the positive implications of nano-sized CLnA formulations which showed higher efficacy over micron-sized systems, irrespective of the fact that the composition of all the formulations was maintained constant. Additionally, real-time flow cytometric data was provided to show that nano-sized bioactive lipids, CLnA, are rapidly internalized and metabolized with enhanced prophylactic and therapeutic effects than micron-sized CLnA.
Funding Organization
Funding Organization

Quick Information
Area of Research
Life Sciences & Biotechnology
Focus Area
Nutrition
Start Year
2011
End Year
2014
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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