Exploring the clinically relevant notch1 mutations in south Indian T-acute lymphoblastic leukemia
Implementing Organization
All India Institute of Medical Sciences
Principal Investigator
Dr. A. Srinivasan
Professor
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All India Institute of Medical Sciences
Project Overview
Identified proteins from present study have been found play a crucial role in apoptosis. Identification of gentamicin-specific-binding eukaryotic proteins might underlie the nephrotoxicity, hepatotoxicity and neurotoxicity caused by this antibiotic and thus can lead to development of potential therapeutic approaches for improving the efficacy of the drug.