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Investigation on the mode of substrate addition with reference to some steroid biotransformation reactions

Implementing Organization

North Eastern Hill University
Principal Investigator
Dr. Timir Tripathi
Assistant Professor
|
North Eastern Hill University

Project Overview

The thiol-based redox-sensitive proteins of the F. gigantica mitochondrial Trx (FgTrx2) is of 16kDa, whereas FgTrx1 is 11.5 kDa molecular weight with active site –WCTPC-, while the other mitochondrial Trx have –WCGPC- or –WCNPC-, none of mitochondrial Trx have –WCTPC- active site motif. Presently, the redox reaction metabolism signifies an important for drug target development, and it has not been studies elaborately in any platyhelminthic parasitic. Hear we plane to characterize FgTrx2 protein in detail to understand the redox biology of this neglected tropical parasite.

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Funding Organization
Funding Organization

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Quick Information
Area of Research
Medical Sciences
Focus Area
Biochemistry
Start Year
2015
End Year
2016
Status
Completed
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
N/A
Startup (If Any)
00
No. of Patents
Filed :00
Grant :00
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