QSAR, docking and ADMET studies on terpenoids and its derivatives for antifungal activity
Implementing Organization
All India Institute of Medical Sciences
Principal Investigator
Dr. A. Srinivasan
Professor
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All India Institute of Medical Sciences
CO-Principal Investigator
Dr. Savita Yadav
Professor
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All India Institute of Medical Sciences
Project Overview
TUBB and SNAP25 reduction could be an early event occurring in the disease. Soluble amyloid beta interacting YWHAZ may disrupt synaptic function and lead to loss in learning and memory causing AD. These results may help in finding the suitable drug targets and more importantly in understanding the disease mechanism.