Screening probiotics and prebiotics for expression of glucagon like Peptide-1 (Glp-1)-A satiety inducing hormone, as probhylactics against diabetes mellitus 2
Implementing Organization
Kasturba Medical College (KMC), Manipal, Karnataka 576104
Principal Investigator
Dr. Guruprasad Kalthur
Professor
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Kasturba Medical College (KMC), Karnataka
CO-Principal Investigator
Dr. Satish Kumar Adiga
Professor
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Kasturba Medical College (KMC), Manipal, Karnataka 576104
Project Overview
Biotin supplementation to the sperm wash medium appears to be beneficial in enhancing the sperm motility and in vitro sperm survival without affecting the fertilizing ability. Beneficial effect of biotin on pre-implantation embryo development ensures that it is safe to used in ART set up. Further experiments are necessary to understand the mechanism of action of biotin in enhancement of sperm function and pre-implantation embryo development. Since biotin is an essential micronutrient, it may be a safe sperm motility enhancing agent than PTX.