Synthesis, biological evaluation and docking studies of some novel heterocyclic compounds

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Implementing Organization

Jamia Millia Islamia

Principal Investigator

Prof. Amir Azam

Professor

Jamia Millia Islamia

About

Thirty-two compounds were synthesized and characterized by various spectroscopic techniques. The results of in vitro antibacterial screening of synthesized compounds revealed fifteen compounds as potent against different bacterial strains. The synthesized compounds were screened in vitro against the promastigote form of Leishmania donovani. The structure of the compounds was established using various spectroscopic techniques and X-ray crystallography was performed for compound 1. The synthesized compounds were screened for their in vitro antimicrobial activity. Further, in silico ADME prediction of synthesized compounds indicated that compounds have a potential to develop as good oral drug candidate

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Area of Research

Chemical Sciences

Focus Area

Heterocyclic Chemistry

End Year

2018

Sanction Amount

₹ NA

Status

Completed

Contact

aazam@jmi.ac.in

Output

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No. of Patents

Filed : 00

Grant : 00

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