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Identification of global metabolite biomarkers in COVID-19 infected patients for targeted therapy

Implementing Organization

Indian Institute of Technology (IIT)
Principal Investigator
Dr Sanjeeva Srivastava
Professor
|
Indian Institute of Technology (IIT), Mumbai

About

The SERB will support exploration of metabolomics alteration in COVID-19-infected patients conducted by IIT Bombay in collaboration with some hospitals in Mumbai. The Study will identify potential biomarker candidates to predict progression from nonsevere to severe COVID-19 conditions. Search for potential diagnostic candidates will involve metabolite profiling of different patient groups with various complications. Metabolites are small biomolecules, capable of regulating various pathways in all the living-organisms. Dr Sanjeeva Srivastava, Professor at IIT Bombay, with the expertise of using state-of-the-art mass spectrometry-based technologies, has teamed up with Dr Om Shrivastav, Director, Infectious Diseases, Jaslok Hospital, Mumbai and Dr Jayanthi S. Shastri, Professor & Head (Microbiology), T N Medical College & Nair Hospital and Dr. Mala Vinod Kaneria, Infectious Disease Specialist at Kasturba, Nair & Jaslok Hospitals, for this research. An advanced mass spectrometry-based national facility equipped with hybrid and tribrid mass spectrometers will facilitate the analysis of nasopharyngeal swab and plasma samples. A team of over 20 researchers having expertise in handling a large number of different types of human biospecimens for proteomics and metabolomics investigations will work on it.
Funding Organization
Funding Organization
Department of Science and Technology (DST)
Quick Information
Focus Area
Drug repurposing for COVID-19
Start Year
2020
Status
Ongoing
Contact
sanjeeva@iitb.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
00
No. of Patents
Filed : 00
Grant : 00
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