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Efficient prediction strategy of COVID-19 based on pandemic data and immunoinformatics, integrated on artificial intelligence (AI) platform

Implementing Organization

Birla Institute of Technology
Principal Investigator
Dr Debashree Bandyopadhyay
Assistant Professor
|
Birla Institute of Technology

About

In this study, COVID-19 detection strategy is developed based on clinical features (blood profiles, cytokines levels etc.) obtained from various hospitals across the globe (published data). This study aims to develop an artificial intelligence platform (deep neural network), where the input data set will include samples from COVID-19 positive patients (mild and severe cases), similar respiratory diseases and healthy controls.

Patents

NA

Achievements

NA

Outcome / Output

Six different datasets were curated with clinical information from two different countries, namely Brazil and Italy. Different haematology parameters were trained to develop machine learning models, based on the datasets. Deep neural network failed on these datasets, as there were a large number of null entries. Hence, machine learning model have been developed based on XGBoost classifier. The performances of the models based on the above six datasets were compared with the performance of reported models. Four hematology parameters identified, namely, leukocyte, eosinophil, monocyte and platelet count, can distinguish COVID-19 infection from five other similar respiratory viruses, namely, influenza A (H1N1), influenza B, coronavirus N63, rhinovirus and respiratory syntactical virus. Statistical significance tests validated the differences between comorbidities.

Publications

NA
Funding Organization
Funding Organization
Department of Science and Technology (DST)
Quick Information
Focus Area
Mathematical modelling for COVID-19
Start Year
2020
Sanction Amount
₹ NA
Status
Ongoing
Contact
banerjee.debi@hyderabad.bits-pilani.ac.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
No. of Patents
Filed : 00
Grant : 00
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