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Towards development of a potent antiviral against SARS–CoV-2 by targeting the interaction between nucleocapsid protein and viral RNA

Implementing Organization

Translational Health Science and Technology Institute (THSTI)
Principal Investigator
Dr Milan Surjit
Associate Professor
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Translational Health Science and Technology Institute (THSTI)

About

The study aims to explore novel therapeutic strategies against the COVID-19 by investigating the role of viral Nucleocapsid protein (N) in the life cycle of SARS-CoV-2 in two steps.

Patents

NA

Achievements

NA

Outcome / Output

Cyclic peptides are one of the most promising therapeutic options, given that many of the existing drugs such as oxytocin, vasopressin (hormones), vancomycin, daptomycin (antibiotics) or cyclosporine (immunosuppressant) are cyclic peptides. Therefore, an inhibitor identified in the study holds significant therapeutic value for SARS-CoV-2.

Publications

NA
Funding Organization
Funding Organization
Department of Science and Technology (DST)
Quick Information
Focus Area
COVID-19 Therapeutics
Start Year
2020
Sanction Amount
₹ NA
Status
Ongoing
Contact
milan@thsti.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
No. of Patents
Filed : 00
Grant : 00
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