Discovery of structure-based antivirals against SARS-CoV-2 targeting key viral genome replication enzymes
Implementing Organization
Indian Institute of Technology (IIT)
Principal Investigator
Prof Pravindra Kumar
Indian Institute of Technology (IIT) Roorkee
About
The project proposes to use structure-based screening of antivirals against SARS- CoV-2 targeting key viral genome replication enzymes such as viral protease that are responsible for the cleavage of non-structural polyprotein and their activation; RNA dependent RNA polymerse as it carries out both primer-independent and primer-dependent synthesis of viral RNA; and G-N7-MTase (nsp14) responsible for camouflaging and obscuring viral RNA from host cell sensing machinery.
Disclaimer:
Information available on this portal is sourced from various organizations and is provided for informational purposes only. Users are advised to verify details from the respective official sources.
Please enter your details
Please provide your name and email to continue. Your details are saved in this browser for future use.
Latest Updates
Loading…
⚠️
You are leaving this website
You are about to be redirected to an external website that is not operated by
India Science, Technology & Innovation (ISTI) Portal.
Indian Institute of Technology (IIT)
Acces sibility Controls