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A rapid approach to generate immortalised B cells for monoclonal antibody generation from SARS-CoV-2 recovered and vaccinated group

Implementing Organization

Rajiv Gandhi Centre for Biotechnology (RGCB)
Principal Investigator
Dr TR Santhosh Kumar
Scientist
|
Rajiv Gandhi Centre for Biotechnology (RGCB)

About

This study aims to identify subset of COVID-19 recovered patients and immunised volunteers with high titer neutralising antibodies for the in vitro B cell immortalisation for neutralising antibody generation.

Patents

NA

Achievements

NA

Outcome / Output

The antibody response heterogeneity reported in COVID-19 infected patient and immunised population is huge. The potential utility of such repertoire of antibodies with viral neutralising activity is yet to be fully exploited for diagnostic or therapeutic purpose. This requires a high efficient approach to identify high neutralising antibody response and selection and expansion of respective B cells producing antibodies.

Publications

NA

Related Research

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Funding Organization
Funding Organization
Department of Biotechnology (DBT)
Quick Information
Focus Area
Monoclonal antibody generation
Start Year
2020
Sanction Amount
₹ NA
Status
Ongoing
Contact
trsanthosh@rgcb.res.in
Output
No. of Research Paper
00
Technologies (If Any)
00
No. of PhD Produced
NA
No. of Patents
Filed : 00
Grant : 00
Disclaimer: Information available on this portal is sourced from various organizations and is provided for informational purposes only. Users are advised to verify details from the respective official sources.
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